Understanding the lipid-digestion Processes in the GI Tract Before Designing lipid-based drug-delivery Systems
- 19 December 2011
- journal article
- review article
- Published by Taylor & Francis in Therapeutic Delivery
- Vol. 3 (1) , 105-124
Abstract
Many of the compounds present in lipid-based drug-delivery systems are esters, such as acylglycerols, phospholipids, polyethyleneglycol mono- and di-esters and polysorbate, which can be hydrolyzed ...Keywords
This publication has 164 references indexed in Scilit:
- In vitro lipolysis models as a tool for the characterization of oral lipid and surfactant based drug delivery systemsInternational Journal of Pharmaceutics, 2011
- Kinetic properties of mouse pancreatic lipase-related protein-2 suggest the mouse may not model human fat digestionJournal of Lipid Research, 2011
- The Structure of Truncated Recombinant Human Bile Salt-stimulated Lipase Reveals Bile Salt-independent Conformational Flexibility at the Active-site Loop and Provides Insights into Heparin BindingJournal of Molecular Biology, 2001
- Pancreatic lipase-related protein 2 but not classical pancreatic lipase hydrolyzes galactolipidsBiochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1996
- Human milk bile salt-stimulated lipase: Functional and molecular aspectsThe Journal of Pediatrics, 1994
- Isoform purification of gastric lipasesJournal of Molecular Biology, 1992
- Importance of human gastric lipase for intestinal lipolysis: an in vitro studyBiochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1986
- Substrate specificity of two cationic lipases with high phospholipase A1, activity purified from guinea pig pancreas II. Studies on glycerophospholipidsBiochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1984
- Pancreatic phospholipase A2 hydrolysis of phosphatidylcholines in various physicochemical statesBiochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1980
- Action of some effectors on the hydrolysis of long-chain triglycerides by pancreatic lipaseBiochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1968