Abstract
The possible biochemical modes of action of levamisole, morantel, benzimidazoles and salicylanilides are discussed. It is concluded that the modes of action of none of these anthelmintics is properly understood, but it seems likely that levamisole and pyrantel act on the nematode nervous system, benzimidazoles affect cellular integrity and the uncoupling properties of salicylanilides could enable them to act at several sites.

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