The biochemical mode of action of some modern anthelmintics
Author:
- 1 October 1977
- journal article
- research article
- Published by Wiley in Pesticide Science
- Vol. 8 (5) , 536-543
Abstract
The possible biochemical modes of action of levamisole, morantel, benzimidazoles and salicylanilides are discussed. It is concluded that the modes of action of none of these anthelmintics is properly understood, but it seems likely that levamisole and pyrantel act on the nematode nervous system, benzimidazoles affect cellular integrity and the uncoupling properties of salicylanilides could enable them to act at several sites.Keywords
This publication has 58 references indexed in Scilit:
- Anthelmintic activity of albendazole against liver flukes, tapeworms, lung and gastrointestinal roundwormsCellular and Molecular Life Sciences, 1976
- Efficacy of levamisole against inhibited larvae of Ostertagia spp in sheepVeterinary Record, 1976
- The successful removal of inhibited fourth stage Ostertagia ostertagi larvae by fenbendazoleVeterinary Record, 1976
- The mechanism of action of the anthelmintic levamisoleGeneral Pharmacology: The Vascular System, 1975
- The efficacy of fenbendazole in the control of trematodes and cestodes1975
- Zur Wirksamkeit von Fenbendazol1 gegen adulte und immature Stadien von Nematospiroides dubius und Heterakis spumosa2Zentralblatt für Veterinärmedizin Reihe B, 1975
- The mode of action of four anthelminticsCellular and Molecular Life Sciences, 1974
- The effects of anthelmintics on nematode metabolismComparative and General Pharmacology, 1970
- The biochemical mechanism of action of the anthelmintic drug tetramisoleLife Sciences, 1967
- Oxyclozanide (3,3',5,5',6-pentachloro-2,2'-dihydroxybenzanilide--6Zanil") in the treatment of the liver fluke Fasciola hepatica in sheep and cattleVeterinary Record, 1966