Prenylagaramides A and B, New Cyclic Peptides from Two Strains of Oscillatoria agardhii
Authors:
- 1 April 1999
- journal article
- research article
- Published by American Chemical Society (ACS) in Journal of Natural Products
- Vol. 62 (5) , 752-755
Abstract
Prenylagaramides A (1) and B (2), two new cyclic peptides, were isolated from the cultured cyanobacteria Oscillatoria agardhii (NIES-205) and O. agardhii (NIES-596), respectively. The structures of 1 and 2, which both contain a rare O-prenyltyrosine (Ptyr) unit, were established as cyclo(-Ptyr 1-Gly 2-Thr 3-Gly 4-Glu 5-Phe 6-Phe 7-Asn 8-Pro 9-) and cyclo(-Ptyr1-Leu2-Tyr3-Pro4-Ile5-Asn6-Pro7-), respectively, by spectroscopic analysis and chemical degradation.Keywords
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