EARLY MORPHOLOGIC CHANGES IN THE INTESTINE FOLLOWING MASSIVE RESECTION OF THE SMALL-INTESTINE AND PARENTERAL-NUTRITION THERAPY

Authors:
  • CSC S Shin
    C S Shin
  • ACA G Chaudhry
    A G Chaudhry
  • MKM H Khaddam
    M H Khaddam
  • PPP D Penha
    P D Penha
  • RDR Dooner
    R Dooner
Google Scholar
  • 1 January 1980
    • journal article
    • research article
    • Vol. 151  (2) , 246-250
    • PMID:6773165
Abstract
Following massive resection of the small intestine, including the ileocecal valve in 7 adult mongrel dogs, the remaining 20 cm of the proximal part of the jejunum was anastomosed to the midtransverse portion of the colon. All dogs were given parenteral nutrition for 4 wk. Six weeks after resection the dogs underwent reexploration, and gross and microscopic examinations of the remaining part of the jejunum were carried out. Grossly, there was a 29.5% increase in the length and a 31% increase in the circumference of the intestine. Microscopically, there was a 23% increase in the depth of the crypts, a 21% increase in the number of villi and a 22% increase in the width of the villi. No change was observed in the height of the villi.