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  3. Supplementary Figure 4 from Lipophilic Statins Deplete GPX4 to Promote Ferroptosis and Sensitize Cancer Cells to Immune Checkpoint Blockade
  1. Home
  2. Publications
  3. Supplementary Figure 4 from Lipophilic Statins Deplete GPX4 to Promote Ferroptosis and Sensitize Cancer Cells to Immune Checkpoint Blockade

Supplementary Figure 4 from Lipophilic Statins Deplete GPX4 to Promote Ferroptosis and Sensitize Cancer Cells to Immune Checkpoint Blockade

Authors:
  • RTRonan Talty
    Ronan Talty
  • VBVeronica T. Brooks
    Veronica T. Brooks
  • MMMeaghan K. McGeary
    Meaghan K. McGeary
  • SMSimon Milette
    Simon Milette
  • SZSijin Zheng
    Sijin Zheng
  • KFKarine Flem-Karlsen
    Karine Flem-Karlsen
  • ADAndrew Daniels
    Andrew Daniels
  • MDMaya Deshmukh
    Maya Deshmukh
  • KPKoonam Park
    Koonam Park
  • WCWill Caraccio
    Will Caraccio
  • HYHong Yan
    Hong Yan
  • CECaroline Echeandia-Francis
    Caroline Echeandia-Francis

Open Access
Publisher website
Google Scholar
  • 17 June 2026
    • other
    • Published by American Association for Cancer Research (AACR)
    • DOI:10.1158/1535-7163.32710142
Abstract
Statins suppress GPX4 expression and mevalonate rescues statin-induced cell death
Keywords
  • SUPPLEMENTARY FIGURE
  • STATINS DEPLETE
  • PROMOTE FERROPTOSIS
  • SENSITIZE CANCER
  • IMMUNE CHECKPOINT
  • CHECKPOINT BLOCKADE
  • LIPOPHILIC STATINS
  • BLOCKADE STATINS
  • STATINS SUPPRESS
  • CANCER CELLS
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