Genomic pathway alterations and their prognostic impact in biliary tract cancer: Insights from a multinational cohort treated with cisplatin, gemcitabine, and durvalumab
- 4 October 2025
- journal article
- Published by Elsevier in European Journal of Cancer
- Vol. 230, 116035
Abstract
No abstract availableKeywords
Funding Information
- AstraZeneca
- Bayer
This publication has 32 references indexed in Scilit:
- Combined Chemotherapy-Immunotherapy for Advanced Biliary Tract Cancer (BTC): A Clinical, Genomic, and Biomarker AnalysisJournal of Gastrointestinal Cancer, 2025
- ESMO Clinical Practice Guideline interim update on the management of biliary tract cancerESMO Open, 2024
- Different Genomic Clusters Impact on Responses in Advanced Biliary Tract Cancer Treated with Cisplatin Plus Gemcitabine Plus DurvalumabTargeted Oncology, 2024
- Pembrolizumab in combination with gemcitabine and cisplatin compared with gemcitabine and cisplatin alone for patients with advanced biliary tract cancer (KEYNOTE-966): a randomised, double-blind, placebo-controlled, phase 3 trialThe Lancet, 2023
- Charting co-mutation patterns associated with actionable drivers in intrahepatic cholangiocarcinomaJournal of Hepatology, 2022
- Biliary tract cancer: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-upAnnals of Oncology, 2022
- Biomarkers for response to immunotherapy in hepatobiliary malignanciesHepatobiliary & Pancreatic Diseases International, 2022
- Gene mutational profile of BRCAness and clinical implication in predicting response to platinum-based chemotherapy in patients with intrahepatic cholangiocarcinomaEuropean Journal of Cancer, 2022
- Real-world application of tumor mutational burden-high (TMB-high) and microsatellite instability (MSI) confirms their utility as immunotherapy biomarkersESMO Open, 2021
- Global trends in mortality from intrahepatic and extrahepatic cholangiocarcinomaJournal of Hepatology, 2019