Dominant negative interference of transcription factor AP-2 causes inhibition of ErbB-3 expression and suppresses malignant cell growth
- 1 January 2002
- journal article
- Published by Springer Nature in Breast Cancer Research and Treatment
- Vol. 71 (1) , 47-57
Abstract
ErbB-3 (HER3) is a member of the epidermal growth factor receptor family. Increasing evidence suggests that elevated expression of ErbB-3 is important for malignancy. In this study, we found that...Keywords
This publication has 36 references indexed in Scilit:
- Transcription Factor AP-2α Is Preferentially Cleaved by Caspase 6 and Degraded by Proteasome during Tumor Necrosis Factor Alpha-Induced Apoptosis in Breast Cancer CellsMolecular and Cellular Biology, 2001
- Transcriptional Factor AP-2γ Increases Human Cystatin A Gene Transcription of KeratinocytesBiochemical and Biophysical Research Communications, 2000
- Anti-sense suppression of epidermal growth factor receptor expression alters cellular proliferation, cell-adhesion and tumorigenicity in ovarian cancer cellsInternational Journal of Cancer, 2000
- Characterization of the Activation Domains of AP-2 Family Transcription FactorsJournal of Biological Chemistry, 2000
- Transcription factor AP‐2 activity is modulated by protein kinase A‐mediated phosphorylationFEBS Letters, 1999
- AP-2 may contribute to IGF-II overexpression in rhabdomyosarcomaOncogene, 1998
- Chromosomal Mapping of the Human and Mouse Homologues of Two New Members of the AP-2 Family of Transcription FactorsGenomics, 1996
- Localization of the gene for the DNA-binding protein AP-2 to human chromosome 6p22.3-pterGenomics, 1991
- Characterization of a Dimerization Motif in AP-2 and Its Function in Heterologous DNA-Binding ProteinsScience, 1991
- Human Breast Cancer: Correlation of Relapse and Survival with Amplification of the HER-2/neuOncogeneScience, 1987