Suppression of Transcription Termination by Phage Lambda
Authors:
- 28 May 1982
- journal article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 216 (4549) , 946-951
Abstract
The bacteriophage lambda N gene product positively controls development by preventing termination of transcription at terminator sites critical to the sequential expression of phage genes. Many host transcription factors, including RNA polymerase, are involved in N gene action. Recent findings have shown that ribosomal proteins are also involved. The current understanding of how the N protein affects transcription termination is reviewed, and a possible model and current problems are discussed.Keywords
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