Evaluating the sensitization potential of surfactants: Integrating data from the local lymph node assay, guinea pig maximization test, and in vitro methods in a weight-of-evidence approach
Authors:
- Stuart CagenSCStuart Cagen
- Juan-Carlos CarrilloJCJuan-Carlos Carrillo
- Hans CertaHCHans Certa
- Dorothea EiglerDEDorothea Eigler
- Roger EmterRERoger Emter
- Frank FaulhammerFFFrank Faulhammer
- Christine GarciaCGChristine Garcia
- Cynthia GrahamCGCynthia Graham
- Carl HauxCHCarl Haux
- Susanne N. KolleSKSusanne N. Kolle
- Reinhard KreilingRKReinhard Kreiling
- 1 August 2011
- journal article
- Published by Elsevier in Regulatory Toxicology and Pharmacology
- Vol. 60 (3) , 389-400
Abstract
No abstract availableKeywords
Funding Information
- European Committee of Organic Surfactants and their Intermediates (CESIO)
- and Givaudan Schweiz AG
- Adama Traore
- Nicole Frijus-Plessen
- Hans Gfeller
- Joachim Schmid
- Thierry Granier (Givaudan Bioscience)
This publication has 29 references indexed in Scilit:
- Comparative testing for the identification of skin-sensitizing potentials of nonionic sugar lipid surfactantsRegulatory Toxicology and Pharmacology, 2010
- Irritant and Sensitizing Potential of Eight Surfactants Commonly Used in Skin Cleansers: An Evaluation of 105 PatientsDermatitis®, 2010
- Performance of a novel keratinocyte-based reporter cell line to screen skin sensitizers in vitroToxicology and Applied Pharmacology, 2010
- Application of a weight of evidence approach to assessing discordant sensitisation datasets: Implications for REACHRegulatory Toxicology and Pharmacology, 2009
- Nothing is perfect, not even the local lymph node assay: a commentary and the implications for REACHContact Dermatitis, 2009
- Development of an in vitro skin sensitization test using human cell lines: The human Cell Line Activation Test (h-CLAT)Toxicology in Vitro, 2006
- Differential Regulation of Epidermal Langerhans Cell Migration by Interleukins (IL)-1α and IL-1β during Irritant- and Allergen-Induced Cutaneous Immune ResponsesToxicology and Applied Pharmacology, 2002
- ICCVAM Evaluation of the Murine Local Lymph Node AssayRegulatory Toxicology and Pharmacology, 2001
- Differential expression and release of cytokines by an in vitro reconstructed human epidermis following exposure to skin irritant and sensitizing chemicalsToxicology in Vitro, 1999
- Normal keratinization in a spontaneously immortalized aneuploid human keratinocyte cell line.Journal of Cell Biology, 1988