Population Analysis of the Pharmacokinetic Variability of High-Dose Metoclopramide in Cancer Patients1
Authors:
- 1 January 1988
- journal article
- research article
- Published by Springer Nature in Clinical Pharmacokinetics
- Vol. 14 (1) , 52-63
Abstract
Metoclopramide infusions are used to prevent nausea and vomiting in cancer patients during chemotherapy. 47 patients received metoclopramide during 109 chemotherapeutic treatments as a loading (dose...Keywords
This publication has 20 references indexed in Scilit:
- Optimising antiemesis in cancer chemotherapy: efficacy of continuous versus intermittent infusion of high dose metoclopramide in emesis induced by cisplatin.BMJ, 1986
- The pharmacokinetics of high dose metoclopramide in patients with neoplastic disease.British Journal of Clinical Pharmacology, 1985
- Improved benefit/risk ratio of higher-dose metoclopramide therapy during cisplatin-induced emesisEuropean Journal of Clinical Pharmacology, 1985
- Pharmacokinetics and efficacy of high‐dose metoclopramide given by continuous infusion for the control of cytotoxic drug‐induced vomiting.British Journal of Clinical Pharmacology, 1984
- Optimizing Metoclopramide Control of Cisplatin-Induced EmesisAnnals of Internal Medicine, 1984
- Extrapyramidal Reactions with High-Dose MetoclopramideNew England Journal of Medicine, 1983
- Evaluation of methods for estimating population pharmacokinetic parameters. III. Monoexponential model: Routine clinical pharmacokinetic dataJournal of Pharmacokinetics and Biopharmaceutics, 1983
- MetoclopramideDrugs, 1983
- Evaluation of methods for estimating population pharmacokinetic parameters II. Biexponential model and experimental pharmacokinetic dataJournal of Pharmacokinetics and Biopharmaceutics, 1981
- Estimation of population characteristics of pharmacokinetic parameters from routine clinical dataJournal of Pharmacokinetics and Biopharmaceutics, 1977