Synthesis of Aromatic Aminosulfonic Acid Nitroamides

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  • KMKazimierz Minksztym
    Kazimierz Minksztym
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Abstract
Nitration of aromatic aminosulfonic acid primary amides to furnish the corresponding sulfononitroamides has been described for the first time. The conditions of nitration applied ensure chemoselective mononitration and prevent decomposition of the product. Synthesis of dabsyl nitroamide sodium salt, as a potential β-amyloid aggregation inhibitor is also reported.