Nuclear EGFR shuttling induced by ionizing radiation is regulated by phosphorylation at residue Thr654
Authors:
- 6 August 2010
- journal article
- Published by Wiley in FEBS Letters
- Vol. 584 (18) , 3878-3884
Abstract
MINT‐7987956: Karyopherin alpha (uniprotkb:P52294) physically interacts (MI:0915) with EGFR (uniprotkb:P00533) by anti bait coimmunoprecipitation (MI:0006)Keywords
Funding Information
- Deutsche Forschungsgemeinschaft (DI 402/9-1)
- Deutsche Krebshilfe (108938)
This publication has 40 references indexed in Scilit:
- Radiation-induced caveolin-1 associated EGFR internalization is linked with nuclear EGFR transport and activation of DNA-PKMolecular Cancer, 2008
- Validation of HB-EGF and amphiregulin as targets for human cancer therapyBiochemical and Biophysical Research Communications, 2008
- Epidermal growth factor receptor juxtamembrane region regulates allosteric tyrosine kinase activationProceedings of the National Academy of Sciences, 2007
- Identification of EGF receptor C-terminal sequences 1005–1017 and di-leucine motif 1010LL1011 as essential in EGF receptor endocytosisExperimental Cell Research, 2007
- Translational up-regulation of the EGFR by tumor hypoxia provides a nonmutational explanation for its overexpression in human cancerProceedings of the National Academy of Sciences, 2007
- EGFR-targeted anti-cancer drugs in radiotherapy: Preclinical evaluation of mechanismsRadiotherapy and Oncology, 2007
- Role of the Sec61 Translocon in EGF Receptor Trafficking to the Nucleus and Gene ExpressionMolecular Biology of the Cell, 2007
- Cross-talk between Epidermal Growth Factor Receptor and Hypoxia-inducible Factor-1α Signal Pathways Increases Resistance to Apoptosis by Up-regulating Survivin Gene ExpressionJournal of Biological Chemistry, 2006
- DNA‐PK autophosphorylation facilitates Artemis endonuclease activityThe EMBO Journal, 2006
- Threonine Phosphorylation Diverts Internalized Epidermal Growth Factor Receptors from a Degradative Pathway to the Recycling EndosomeJournal of Biological Chemistry, 2000