CT and MR in non-neonatal hypoxic–ischemic encephalopathy: radiological findings with pathophysiological correlations

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Abstract
Non-neonatal hypoxic–ischemic encephalopathy is a clinical condition often related to cardiopulmonary arrest that demands critical management and treatment decisions. Management depends mainly on the degree of neurological impairment and prognostic considerations. Computed tomography (CT) is often used to exclude associated or mimicking pathology. If any, only nonspecific signs such as cerebral edema, sulci effacement, and decreased gray matter (GM)/white matter (WM) differentiation are evident. Pseudosubarachnoid hemorrhage, a GM/WM attenuation ratio N-acetyl aspartate peak on MR spectroscopy, seem to have prognostic value.

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