Effects of Low-Level Persistent Infection on Maintenance of Immunity by CD4 T Cell Subsets and Th1 Cytokines
Open Access
- 15 March 2023
- journal article
- research article
- Published by American Society for Microbiology in Infection and Immunity
- Vol. 91 (3) , e0053122
Abstract
CD4 T cells are required, along with antibodies, for complete protection from blood-stage infection with Plasmodium spp., which cause malaria. Without continuous exposure, as on emigration of people from endemic areas, protection from malaria decays.Keywords
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Funding Information
- HHS | NIH | National Institute of Allergy and Infectious Diseases (R01AI08995304)
- HHS | NIH | National Institute of Allergy and Infectious Diseases (R01AI135061)
- HHS | NIH | National Institute of Allergy and Infectious Diseases (R01AI08995304S01)
- HHS | NIH | National Institute of Allergy and Infectious Diseases (F31AI126809)
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