Cost-effectiveness of fibronectin testing in a triage in women with threatened preterm labor: alleviation of pregnancy outcome by suspending tocolysis in early labor (APOSTEL-I trial)
Authors:
- Jolande Y VisJVJolande Y Vis
- Femke F WilmsFWFemke F Wilms
- Martijn A OudijkMOMartijn A Oudijk
- Martina M PorathMPMartina M Porath
- Hubertina Cj ScheepersHSHubertina Cj Scheepers
- Kitty Wm BloemenkampKBKitty Wm Bloemenkamp
- Annemiek C BolteABAnnemiek C Bolte
- Jérôme CornetteJCJérôme Cornette
- Jan B DerksJDJan B Derks
- Johannes J DuvekotJDJohannes J Duvekot
- Jim van EyckJEJim van Eyck
- Anneke KweeAKAnneke Kwee
Open Access
- 1 September 2009
- journal article
- research article
- Published by Springer Nature in BMC Pregnancy and Childbirth
- Vol. 9 (1) , 38
Abstract
At present, women with threatened preterm labor before 32 weeks of gestation are, after transfer to a perinatal center, treated with tocolytics and corticosteroids. Many of these women are treated unnecessarily. Fibronectin is an accurate predictor for the occurrence of preterm birth among women with threatened preterm labor. We will assess whether triage of these women with fibronectin testing, cervical length or their combination is cost-effective.Keywords
This publication has 23 references indexed in Scilit:
- Adverse drug reactions to tocolytic treatment for preterm labour: prospective cohort studyBMJ, 2009
- Fetal fibronectin testing for reducing the risk of preterm birthCochrane Database of Systematic Reviews, 2008
- Transvaginal sonographic measurement of cervical length to predict preterm birth in asymptomatic women at increased risk: a systematic reviewUltrasound in Obstetrics & Gynecology, 2008
- Does knowledge of cervical length and fetal fibronectin affect management of women with threatened preterm labor? A randomized trialAmerican Journal of Obstetrics and Gynecology, 2007
- Severe hypotension and fetal death due to tocolysis with nifedipineBJOG: An International Journal of Obstetrics & Gynaecology, 2005
- Cervicovaginal fibronectin improves the prediction of preterm delivery based on sonographic cervical length in patients with preterm uterine contractions and intact membranesAmerican Journal of Obstetrics and Gynecology, 2005
- Does fetal fibronectin use in the diagnosis of preterm labor affect physician behavior and health care costs? A randomized trialAmerican Journal of Obstetrics and Gynecology, 2004
- Repeated antenatal corticosteroids: Effects on cerebral palsy and childhood behaviorAmerican Journal of Obstetrics and Gynecology, 2004
- Prospective randomized controlled trial of fetal fibronectin on preterm labor management in a tertiary care centerAmerican Journal of Obstetrics and Gynecology, 2004
- Calcium channel blockers for inhibiting preterm labour2003