Octopamine-Sensitive Adenylate Cyclase: Evidence for a Biological Role of Octopamine in Nervous Tissue
Authors:
- 20 April 1973
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 180 (4083) , 308-310
Abstract
An adenylate cyclase that is activated specifically by very low concentrations of octopamine has been identified both in homogenates and in intact cells of the thoracic ganglia of an insect nervous system. This enzyme appears to be distinct from two other adenylate cyclases present in the same tissue, which are activated by dopamine and by 5-hydroxytryptamine, respectively. The data raise the possibility of a role of octopamine-sensitive adenylate cyclase in the physiology of synaptic transmission.Keywords
This publication has 12 references indexed in Scilit:
- Activation of insect nerve cord phosphorylase by octopamine and adenosine 3′,5′‐monophosphateJournal of Neurochemistry, 1972
- Biosynthesis of Cerebral Phenolic Amines. I. In Vivo Formation of p-Tyramine, Octopamine, and SynephrineCanadian Journal of Biochemistry, 1972
- DISTRIBUTION AND TURNOVER OF OCTOPAMINE IN TISSUESJournal of Neurochemistry, 1972
- Dopamine-Sensitive Adenyl Cyclase: Possible Role in Synaptic TransmissionScience, 1971
- Transmitter substances in insects: A reviewComparative and General Pharmacology, 1971
- FALSE NEUROTRANSMITTERS AND HEPATIC FAILUREThe Lancet, 1971
- β-hydroxylation of tyramine by cockroach hemolymphBiochimica et Biophysica Acta (BBA) - General Subjects, 1970
- Iontophoretic application of acetylcholine and gaba onto insect central neuronesComparative Biochemistry and Physiology, 1969
- New Evidence for the Control Mechanism of Sclerotization in InsectsNature, 1969
- Cyclic Adenosine Monophosphate: Possible Mediator for Norepinephrine Effects on Cerebellar Purkinje CellsScience, 1969