Fawcettimine‐Type Lycopodium Alkaloids as a Driving Force for Discoveries in Organic Synthesis
Authors:
- 18 December 2017
- journal article
- research article
- Published by Wiley in The Chemical Record
- Vol. 18 (5) , 543-554
Abstract
Ever since the pioneering synthetic work reported by both Inubushi and Heathcock back in 1980s, the fawcettimine‐type Lycopodium alkaloids have continuously served as a driving force for discoveries in organic synthesis. In this personal account, we summarized our recent synthetic efforts towards the total synthesis of fawcettimine‐type Lycopodium alkaloids, along with a brief summary of relevant syntheses reported by others. Our discussions focus mainly on the key reactions applied during the synthesis of fawcettimine‐type Lycopodium alkaloids.Keywords
Funding Information
- National Key Research and Development Program of China (2017YFA0505200)
- National High Technology Project 973 (2015CB856200)
- NNSFC (21472010, 21521003, 21561142002, 21625201)
This publication has 86 references indexed in Scilit:
- Total Synthesis of (−)‐Lycoposerramine‐SAngewandte Chemie International Edition, 2012
- Unified Total Syntheses of Fawcettimine Class Alkaloids: Fawcettimine, Fawcettidine, Lycoflexine, and Lycoposerramine BThe Journal of Organic Chemistry, 2012
- Palhinine A, a Novel Alkaloid from Palhinhaea cernuaOrganic Letters, 2010
- Total Synthesis of (+)-Sieboldine AJournal of the American Chemical Society, 2010
- Total Synthesis of (+)-Complanadine A Using an Iridium-Catalyzed Pyridine C−H FunctionalizationJournal of the American Chemical Society, 2010
- Total Synthesis of the Lycopodium Alkaloid (+)-Serratezomine AJournal of the American Chemical Society, 2009
- Total syntheses of the lycopodium alkaloids (.+-.)-fawcettimine and (.+-.)-8-deoxyserratinine.Chemical and Pharmaceutical Bulletin, 1980
- Total synthesis of the lycopodium alkaloid dl-serratinine.Chemical and Pharmaceutical Bulletin, 1975
- The Plane Structure of SerratinineChemical and Pharmaceutical Bulletin, 1968
- Serratinine ; A Novel Skeletal Lycopodium AlkaloidChemical and Pharmaceutical Bulletin, 1968