Implementation of a lifestyle and life‐skills intervention to prevent weight‐gain and cardiometabolic abnormalities in young people with first‐episode psychosis as part of routine care: The Keeping the Body in Mind program
Open Access
- 9 February 2024
- journal article
- research article
- Published by Wiley in Early Intervention in Psychiatry
- Vol. 18 (9) , 731-738
Abstract
Objectives: In 2013, a cluster‐controlled pilot study found the 12‐week Keeping the Body in Mind (KBIM) lifestyle and life skills intervention was able to prevent weight gain in a small sample of youth experiencing first‐episode psychosis (FEP) with fewer than 4 weeks of antipsychotic exposure. This study aims to evaluate the effectiveness of KBIM as routine care on anthropometry and metabolic biochemistry in a larger sample of youth with FEP across three community mental health services.Method: This retrospective chart audit was conducted on youth with FEP, prescribed a therapeutic dose of antipsychotic medication, and who engaged with KBIM between 2015 and 2019. Primary outcomes were weight and waist circumference. Secondary outcomes were blood pressure, blood glucose, and blood lipids. Outcomes were collected in at baseline and at 12 weeks. Data on program engagement were obtained from the participant's medical file.Results: One‐hundred and eighty‐two people met inclusion criteria, and up to 134 people had baseline and 12‐week data on one or more outcome. Mean number of sessions attended was 11.1 (SD = 7.3). Increases in weight and waist circumference were limited to 1.5 kg (SD = 5.3, t(133) = 3.2, p = .002) and 0.7 cm (SD = 5.8, t(109) = 1.2, p = .23) respectively. Eighty‐one percent of participants did not experience clinically significant weight gain (>7% of baseline weight). There were no significant changes in blood pressure or metabolic biochemistry.Conclusion: The prevention of substantial gains in weight and waist circumference observed in the initial pilot study was maintained with implementation of KBIM as part of routine clinical care for youth with FEP.Keywords
This publication has 21 references indexed in Scilit:
- Development and external validation of the Psychosis Metabolic Risk Calculator (PsyMetRiC): a cardiometabolic risk prediction algorithm for young people with psychosisThe Lancet Psychiatry, 2021
- The Lancet Psychiatry Commission: a blueprint for protecting physical health in people with mental illnessThe Lancet Psychiatry, 2019
- Lifestyle interventions for weight loss among overweight and obese adults with serious mental illness: A systematic review and meta-analysisGeneral Hospital Psychiatry, 2017
- Prevalence, incidence and mortality from cardiovascular disease in patients with pooled and specific severe mental illness: a large‐scale meta‐analysis of 3,211,768 patients and 113,383,368 controlsWorld Psychiatry, 2017
- Years of potential life lost and life expectancy in schizophrenia: a systematic review and meta-analysisThe Lancet Psychiatry, 2017
- The effects of antipsychotics on weight gain, weight-related hormones and homocysteine in children and adolescents: a 1-year follow-up studyEuropean Child & Adolescent Psychiatry, 2016
- Cardiometabolic health in young people with psychosisThe Lancet Psychiatry, 2014
- Second-Generation Antipsychotic Use in Children and Adolescents: A Six-Month Prospective Cohort Study in Drug-Naïve PatientsJournal of the American Academy of Child & Adolescent Psychiatry, 2014
- Efficacy of metformin for prevention of weight gain in psychiatric populationsInternational Clinical Psychopharmacology, 2012
- Cardiometabolic Risk of Second-Generation Antipsychotic Medications During First-Time Use in Children and AdolescentsJAMA, 2009