Design, synthesis and biological evaluation of carbamate derivatives incorporating multifunctional carrier scaffolds as pseudo-irreversible cholinesterase inhibitors for the treatment of Alzheimer's disease
Authors:
- 21 December 2023
- journal article
- research article
- Published by Elsevier in European Journal of Medicinal Chemistry
- Vol. 265, 116071
Abstract
No abstract availableKeywords
Funding Information
- Scientific Research Fund of Liaoning Provincial Education Department (LJKMZ20221368)
- Department of Education of Liaoning Province
This publication has 45 references indexed in Scilit:
- Carbamate Derivatives of Indolines as Cholinesterase Inhibitors and Antioxidants for the Treatment of Alzheimer’s DiseaseJournal of Medicinal Chemistry, 2012
- Antioxidant activity of unexplored indole derivatives: Synthesis and screeningEuropean Journal of Medicinal Chemistry, 2010
- Urea and carbamate derivatives of primaquine: Synthesis, cytostatic and antioxidant activitiesBioorganic & Medicinal Chemistry, 2009
- Site-Activated Multifunctional Chelator with Acetylcholinesterase and Neuroprotective−Neurorestorative Moieties for Alzheimer’s TherapyJournal of Medicinal Chemistry, 2009
- Carbamates with Differential Mechanism of Inhibition Toward Acetylcholinesterase and ButyrylcholinesteraseJournal of Medicinal Chemistry, 2008
- Elevated butyrylcholinesterase and acetylcholinesterase may predict the development of type 2 diabetes mellitus and Alzheimer’s diseaseMedical Hypotheses, 2007
- Complexes of Alkylene-Linked Tacrine Dimers with Torpedo californica Acetylcholinesterase: Binding of Bis(5)-tacrine Produces a Dramatic Rearrangement in the Active-Site GorgeJournal of Medicinal Chemistry, 2006
- Oxidative Stress Hypothesis in Alzheimer's DiseaseFree Radical Biology and Medicine, 1997
- Changes in acetylcholinesterase and butyrylcholinesterase in Alzheimer's disease resemble embryonic development—A study of molecular formsNeurochemistry International, 1992
- Scopolamine effects on memory retention in mice: A model of dementia?Behavioral and Neural Biology, 1986