Midterm Results of a Combined Biological and Mechanical Approach for the Treatment of a Complex Knee Lesion
Open Access
- 17 July 2012
- journal article
- research article
- Published by SAGE Publications in CARTILAGE
- Vol. 3 (3) , 288-292
Abstract
Objective: Complex fractures of the tibial plateau are difficult to treat and present a high complication rate. The goal of this report is to describe a combined biological and mechanical approach to restore all morphological and functional knee properties. Methods: We treated a 50-year-old woman, who was affected by a posttraumatic osteochondral lesion and depression of the lateral tibial plateau with knee valgus deviation. The mechanical axis was corrected with a lateral tibial plateau elevation osteotomy, the damaged joint surface was replaced by a recently developed biomimetic osteochondral scaffold, and a hinged dynamic external fixator was applied to protect the graft and at the same time to allow postoperative joint mobilization. Results: A marked clinical improvement was documented at 12 months and further improved up to 5 years, with pain-free full range of motion and return to previous activities. The MRI evaluation at 12 and 24 months showed that the implant remained in site with a hyaline-like signal and restoration of the articular surface. Conclusion: This case report describes a combined surgical approach for complex knee lesions that could represent a treatment option to avoid or at least delay posttraumatic osteoarthritis and more invasive procedures.Keywords
This publication has 19 references indexed in Scilit:
- Novel Nano-composite Multilayered Biomaterial for Osteochondral RegenerationThe American Journal of Sports Medicine, 2011
- Platelet autologous growth factors decrease the osteochondral regeneration capability of a collagen-hydroxyapatite scaffold in a sheep modelBMC Musculoskeletal Disorders, 2010
- Novel nanostructured scaffold for osteochondral regeneration: pilot study in horsesJournal of Tissue Engineering and Regenerative Medicine, 2010
- Orderly osteochondral regeneration in a sheep model using a novel nano‐composite multilayered biomaterialJournal of Orthopaedic Research, 2009
- Novel nano‐composite multi‐layered biomaterial for the treatment of multifocal degenerative cartilage lesionsKnee Surgery, Sports Traumatology, Arthroscopy, 2009
- Treatment Strategies for Complex Fractures of the Tibial Plateau With External Circular Fixation and Limited Internal FixationJournal of Trauma: Injury, Infection & Critical Care, 2007
- Osteochondral tissue engineeringJournal of Biomechanics, 2007
- Biologically inspired synthesis of bone‐like composite: Self‐assembled collagen fibers/hydroxyapatite nanocrystalsJournal of Biomedical Materials Research Part A, 2003
- Total knee arthroplasty in post-traumatic arthrosis of the kneeThe Journal of Arthroplasty, 2003
- Tibial Plateau FracturesJournal of Orthopaedic Trauma, 1994