Mechanism of inhibition of DNA gyrase by quinolone antibacterials: a cooperative drug-DNA binding model
Authors:
- Lester A. MitscherLMLester A. Mitscher
- Padam N. SharmaPSPadam N. Sharma
- T. J. O'DonnellTOT. J. O'Donnell
- Daniel W. T. ChuDCDaniel W. T. Chu
- Curt S. CooperCCCurt S. Cooper
- Terry RosenTRTerry Rosen
- Andre G. PernetAPAndre G. Pernet
- 1 May 1989
- journal article
- research article
- Published by American Chemical Society (ACS) in Biochemistry
- Vol. 28 (9) , 3886-3894
Abstract
Note: In lieu of an abstract, this is the article's first page.Keywords
This publication has 33 references indexed in Scilit:
- Interaction between DNA gyrase and its cleavage site on DNA.Journal of Biological Chemistry, 1980
- DNA Gyrase and the Supercoiling of DNAScience, 1980
- DNA gyrase on the bacterial chromosome: DNA cleavage induced by oxolinic acidJournal of Molecular Biology, 1979
- Site-specific cleavage of DNA by E. coli DNA gyraseCell, 1979
- DNA gyrase: subunit structure and ATPase activity of the purified enzyme.Proceedings of the National Academy of Sciences, 1978
- Energy coupling in DNA gyrase and the mechanism of action of novobiocinProceedings of the National Academy of Sciences, 1978
- Purification of subunits of Escherichia coli DNA gyrase and reconstitution of enzymatic activityProceedings of the National Academy of Sciences, 1978
- Nalidixic acid resistance: A second genetic character involved in DNA gyrase activityProceedings of the National Academy of Sciences, 1977
- Mechanism of action of nalidixic acid: Purification of Escherichia coli nalA gene product and its relationship to DNA gyrase and a novel nicking-closing enzymeProceedings of the National Academy of Sciences, 1977
- The interaction of nucleosides in aqueous solutionJournal of Molecular Biology, 1968