Effect of neutral resins on the production of dynemicins byMicromonospora chersina
Authors:
- 1 November 1995
- journal article
- Published by Oxford University Press (OUP) in Journal of Industrial Microbiology and Biotechnology
- Vol. 15 (5) , 453-456
Abstract
Addition of Diaion HP-20 or Amberlite XAD-8 resin to the fermentation ofMicromonospora chersina ATCC 53710 enhanced the production of dynemicin A by 4.7- and 6.9-fold, respectively. Addition of resin suppressed the production of other dynemicin analogs, which comprised 65% of the dynemicin complex in the fermentation.Keywords
This publication has 20 references indexed in Scilit:
- The soraphens: A family of novel antifungal compounds from Sorangium cellulosum (myxobacteria). I. Soraphen A1.ALPHA.: Fermentation, isolation, biological properties.The Journal of Antibiotics, 1994
- The effect of cerulenin on the production of esperamicin A1 byActinomadura verrucososporaJournal of Industrial Microbiology and Biotechnology, 1993
- Improved processes for the production and isolation of dynemicin A and large-scale fermentation in a 10000-liter fermentorJournal of Industrial Microbiology and Biotechnology, 1992
- Sapurimycin, new antitumor antibiotic produced by Streptomyces. Producing organism, fermentation, isolation and biological properties.The Journal of Antibiotics, 1991
- Crystal and molecular structure of dynemicin A: a novel 1,5-diyn-3-ene antitumor antibioticJournal of the American Chemical Society, 1990
- Use of resins for trichothecene production in liquid cultures.The Journal of Antibiotics, 1990
- The kapurimycins, new antitumor antibiotics produced by Strepromyces. Producing organism, fermentation, isolation and biological activities.The Journal of Antibiotics, 1990
- DC 107, a novel antitumor antibiotic produced by a Streptomyces sp.The Journal of Antibiotics, 1989
- Dynemicin A, a novel antibiotic with the anthraquinone and 1,5-diyn-3-ene subunit.The Journal of Antibiotics, 1989
- Esperamicins, a novel class of potent antitumor antibiotics. 3. Structures of esperamicins A1, A2, and A1bJournal of the American Chemical Society, 1987