Cyclic derivative of morphiceptin Dmt-cyclo-(D-Lys-Phe-D-Pro-Asp)-NH2(P-317), a mixed agonist of MOP and KOP opioid receptors, exerts anti-inflammatory and anti-tumor activity in colitis and colitis-associated colorectal cancer in mice
- 1 October 2020
- journal article
- research article
- Published by Elsevier in European Journal of Pharmacology
- Vol. 885, 173463
Abstract
No abstract availableKeywords
Funding Information
- Uniwersytet Medyczny w Lodzi (503/1-156-04/503-11-001-19-00)
- Narodowe Centrum Nauki (-2013/11-N/NZ7/00724)
- Ministerstwo Edukacji i Nauki (1658/MOB/V/2017/0)
This publication has 44 references indexed in Scilit:
- Inhibitory effect of opiates on LPS mediated release of TNF and IL-8Acta Oncologica, 2012
- Chronic intestinal inflammation: inflammatory bowel disease and colitis-associated colon cancerFrontiers in Immunology, 2012
- Pro‐opiomelanocortin gene delivery suppresses the growth of established Lewis lung carcinoma through a melanocortin‐1 receptor‐independent pathwayThe Journal of Gene Medicine, 2011
- Animal research: Reporting in vivo experiments: The ARRIVE guidelinesBritish Journal of Pharmacology, 2010
- Inflammatory bowel disease and intestinal cancer: a paradigm of the Yin–Yang interplay between inflammation and cancerOncogene, 2010
- COX-2 inhibitor celecoxib prevents chronic morphine-induced promotion of angiogenesis, tumour growth, metastasis and mortality, without compromising analgesiaBritish Journal of Cancer, 2007
- Functional Expression of μ-Opioid Receptors in the Human Colon Cancer Cell Line, HT-29, and their Localization in Human ColonDigestive Diseases and Sciences, 2007
- Muc2-Deficient Mice Spontaneously Develop Colitis, Indicating That MUC2 Is Critical for Colonic ProtectionGastroenterology, 2006
- Mu opioid receptor expression is increased in inflammatory bowel diseases: implications for homeostatic intestinal inflammationGut, 2005
- The involvement of nitric oxide in the enhanced expression of μ‐opioid receptors during intestinal inflammation in miceBritish Journal of Pharmacology, 2005