Catalytic Deprotonative Functionalization of Propargyl Silyl Ethers with Imines
- 31 July 2008
- journal article
- research article
- Published by Wiley in Advanced Synthesis & Catalysis
- Vol. 350 (11-12) , 1901-1906
Abstract
A metal‐free, catalytic CH functionalization of propargyl silyl ethers with imines using the phosphazene base (t‐Bu‐P4 base) provides structurally defined multisubstituted pyrroles in modest to excellent yields under mild conditions. A one‐pot, three‐component reaction using silylated acetylenes, aldehydes, and imines is also presented.Keywords
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