Circulating matrix metalloproteinase MMP-9 and MMP-2/TIMP-2 complex are associated with spontaneous early pregnancy failure
Open Access
- 1 January 2013
- journal article
- Published by Springer Nature in Reproductive Biology and Endocrinology
- Vol. 11 (1) , 2
Abstract
Trophoblast cell (CTB) invasion into the maternal endometrium plays a crucial role during human embryo implantation and placentation. This invasion is facilitated by the activity of matrix metalloproteinases, which are regulated by tissue inhibitors of MMPs (TIMPs).Keywords
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