Soft-Tissue Sarcoma

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Abstract
With regard to the article by Clark et al. (Aug. 18 issue),1 we would like to call attention to the usefulness of fine-needle aspiration biopsy for soft-tissue sarcoma. In their article, the authors point out that fine-needle aspiration biopsy is useful for the diagnosis of metastatic or recurrent lesions. Although we concur, we and others2-5 have found this technique to be remarkably reliable in the diagnosis of primary soft-tissue sarcoma. The accurate typing and grading of a large proportion of sarcomas are feasible. This is especially true if additional cellular material is collected by extra needle passes (an advantage of fine-needle aspiration) for immunocytochemical, cytogenetic, and molecular analyses.