Organocatalytic Asymmetric Michael Addition of Rhodanines to Azadienes for Assembling of Sulfur‐containing Tetrasubstituted Carbon Stereocenters
- 19 November 2018
- journal article
- research article
- Published by Wiley in Advanced Synthesis & Catalysis
- Vol. 361 (3) , 476-480
Abstract
The squaramide catalyzed enantioselective Michael addition of rhodanines to 2‐arylidene‐N‐tosylbenzofuran‐3(2H)‐imines has been established, which enables the formation of benzofurans bearing both rhodanine and sulfur‐containing tetrasubstituted stereocenter structural motif in good to high yields with good to excellent enantio‐ and diastereoselectivities. magnified imageKeywords
Funding Information
- National Natural Science Foundation of China (21502043)
- Natural Science Foundation of Shandong Province (ZR2017JL011)
This publication has 39 references indexed in Scilit:
- Catalytic Enantioselective Synthesis of Tertiary Thiols From 5H‐Thiazol‐4‐ones and Nitroolefins: Bifunctional Ureidopeptide‐Based Brønsted Base CatalysisAngewandte Chemie International Edition, 2013
- Transfer of Sulfur: From Simple to DiverseChemistry – An Asian Journal, 2013
- Advances and Applications in Organocatalytic Asymmetric aza‐Michael AdditionChemCatChem, 2012
- Asymmetric Michael Addition of Substituted Rhodanines to α,β-Unsaturated Ketones Catalyzed by Bulky Primary AminesOrganic Letters, 2012
- Asymmetric synthesis of tertiary thiols and thioethersBeilstein Journal of Organic Chemistry, 2011
- Enantioselective Michael Addition ReactionsOrganic Preparations and Procedures International, 2011
- Recent Advances in Asymmetric Organocatalytic 1,4‐Conjugate AdditionsEuropean Journal of Organic Chemistry, 2007
- Asymmetric Sulfa-Michael AdditionsSynthesis, 2007
- Organocatalytic asymmetric conjugate additionsTetrahedron: Asymmetry, 2007
- Conjugate Additions of Nitroalkanes to Electron-Poor Alkenes: Recent ResultsChemical Reviews, 2005