Isolation of tridecaptins A, B and C. Studies on antibiotics from the genus Bacillus. XXIII.

Authors:
  • JSJun''IChi Shoji
    Jun''IChi Shoji
  • HHHiroshi Hinoo
    Hiroshi Hinoo
  • RSRyuzi Sakazaki
    Ryuzi Sakazaki
  • TKToshiyuki Kato
    Toshiyuki Kato
  • YWYoshiharu Wakisaka
    Yoshiharu Wakisaka
  • MMMikao Mayama
    Mikao Mayama
  • SMShinzo Matsuura
    Shinzo Matsuura
  • HMHideaki Miwa
    Hideaki Miwa
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Abstract
Three new antibiotics, tridecaptins A, B and C, were isolated from culture broths of strains of Bacillus polymyxa AR-110, B-2 and E-23, respectively. All are acyl tridecapeptides differing from each other in the fatty acid components and amino acid residues. They are weakly active against Gram-negative and Gram-positive bacteria in vitro and in vivo.