The efficient and regioselective synthesis of the naphthoquinone core of streptovaricin U

Authors:
  • MMMasaaki Miyashita
    Masaaki Miyashita
  • TYTakahiro Yamasaki
    Takahiro Yamasaki
  • TSTomonori Shiratani
    Tomonori Shiratani
  • SHSusumi Hatakeyama
    Susumi Hatakeyama
  • MMMasahiro Miyazawa
    Masahiro Miyazawa
  • HIHiroshi Irie
    Hiroshi Irie
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Abstract
The efficient and regioselective synthesis of the naphthoquinone core of streptovaricin U 1 via the Diels–Alder reaction of 1-methoxy-2-methyl-3-trimethylsilyloxybuta-1,3-diene 5 with the 2,6-dibromo-3-methyl-1,4-benzoquinone 6 is described.