Depressive Symptoms and Severity of Illness in Multiple Sclerosis: Epidemiologic Study of a Large Community Sample
Authors:
- Lydia ChwastiakLCLydia Chwastiak
- Dawn M. EhdeDEDawn M. Ehde
- Laura E. GibbonsLGLaura E. Gibbons
- Mark SullivanMSMark Sullivan
- James D. BowenJBJames D. Bowen
- George H. KraftGKGeorge H. Kraft
- 1 November 2002
- journal article
- research article
- Published by American Psychiatric Association Publishing in American Journal of Psychiatry
- Vol. 159 (11) , 1862-1868
Abstract
OBJECTIVE: Previous research has shown high prevalence rates of depression in multiple sclerosis patients seen in specialty clinics. The relationships among depressive symptoms and severity, duration, and course of multiple sclerosis are controversial. METHOD: A survey was mailed to members of the Multiple Sclerosis Association of King County (Wash.). Of the 1,374 eligible participants, 739 returned the survey, a response rate of 53.8%. Data about demographic characteristics, employment, and duration and course of multiple sclerosis were collected. Severity of multiple sclerosis was determined by the Expanded Disability Status Scale, self-report version. Severity of depressive symptoms was evaluated with the Center for Epidemiologic Studies Depression Scale (CES-D Scale). Analysis of covariance was used to compare mean CES-D Scale scores across categories of multiple sclerosis, and logistic regression was used to identify variables associated with clinically significant depression. RESULTS: Clinically sig...Keywords
This publication has 44 references indexed in Scilit:
- Prevalence, nature, and comorbidity of depressive disorders in primary careGeneral Hospital Psychiatry, 1994
- Depressive symptoms as predictors of medical outcomes in HIV infection. Multicenter AIDS Cohort StudyJAMA, 1993
- An Estimate of the Incidence of Depression in Idiopathic Parkinson's DiseaseArchives of Neurology, 1992
- Physical consequences of depression in the stroke patientGeneral Hospital Psychiatry, 1992
- Depression in multiple sclerosisGeneral Hospital Psychiatry, 1987
- Mood Disorder and Multiple SclerosisArchives of Neurology, 1987
- Assessing Depression in Primary Medical and Psychiatric PracticesArchives of General Psychiatry, 1985
- Behavioral Disorders in Multiple Sclerosis, Temporal Lobe Epilepsy, and Amyotrophic Lateral SclerosisArchives of Neurology, 1984
- Depression in multiple sclerosis as a function of length and severity of illness, age, remissions, and perceived social supportJournal of Clinical Psychology, 1984
- Disease activity and emotional state in multiple sclerosisAnnals of Neurology, 1983