The 1,4-naphthoquinone scaffold in the design of cysteine protease inhibitors
Authors:
- Rui MoreiraRui Moreira
- Rita C. GuedesRita C. Guedes
- Jim IleyJim Iley
- Mohammed JaffarMJMohammed Jaffar
- Kenneth T. DouglasKDKenneth T. Douglas
- 1 August 2007
- journal article
- Published by Elsevier in Bioorganic & Medicinal Chemistry
- Vol. 15 (15) , 5340-5350
Abstract
No abstract availableKeywords
This publication has 42 references indexed in Scilit:
- 2-(Quinazolin-4-ylamino)-[1,4]benzoquinones as Covalent-Binding, Irreversible Inhibitors of the Kinase Domain of Vascular Endothelial Growth Factor Receptor-2Journal of Medicinal Chemistry, 2005
- Quantitative structure–activity relationship in aziridinyl-1,4-naphthoquinone antimalarials: study of theoretical correlations by the PM3 methodBioorganic & Medicinal Chemistry, 2004
- Human and Parasitic Papain-Like Cysteine Proteases: Their Role in Physiology and Pathology and Recent Developments in Inhibitor DesignChemical Reviews, 2002
- Antiparasitic Agent AtovaquoneAntimicrobial Agents and Chemotherapy, 2002
- Cell Growth Inhibition by a Novel Vitamin K Is Associated with Induction of Protein Tyrosine PhosphorylationJournal of Biological Chemistry, 1998
- Cysteine Proteases and Their InhibitorsChemical Reviews, 1997
- Growth Inhibition of Hepatoma Cells Induced by Vitamin K and Its AnalogsJournal of Biological Chemistry, 1995
- Structure-activity relationships for inhibition of papain by peptide Michael acceptorsJournal of Medicinal Chemistry, 1992
- Synthesis and antimalarial activity of 2-aziridinyl- and 2,3-bis(aziridinyl)-1,4-naphthoquinonyl sulfonate and acylate derivativesJournal of Medicinal Chemistry, 1991
- Molecular mechanisms of quinone cytotoxicityChemico-Biological Interactions, 1991