Prevention and Control Strategies for SARS-CoV-2 Infection
- 30 April 2020
- book chapter
- Published by Springer Nature
- p. 127-140
Abstract
The population of 168 countries all over the world is struggling with the outbreak of COVID-19. The outbreak is declared as pandemic and public health emergency of international concern declared by WHO. SARS-CoV-2 responsible for the present health emergency exhibited close resemblance with SARS-CoV. Both the viruses are zoonotic and belong to a large family of viruses Coronaviridae. The complete virus particle is made up of four major structural proteins, namely spikes (S), nucleocapsid (N), membrane (M), and envelope (E) encoded by virus genome. The S protein of virus shows similarity to S protein of SARS-CoV. COVID-19 spreads from person to person, and this makes it more vulnerable for causing infection. Several efforts are taken to find prevention strategies for COVID-19. Researchers across the globe are working to find effective vaccination for SARS-CoV-2. There is no vaccine or medication available till date for COVID-19. Preventive measures such as social distancing, awareness, maintenance of hygiene, isolation, and movement restrictions can help in control of COVID-19 spread. Proper sanitization and cleaned and sanitized public transport can be effective in inhibiting the spread of the virus. In the present situation of medical emergency, cooperation and support by following advices from the WHO and government only facilitate everyone to come over.Keywords
This publication has 26 references indexed in Scilit:
- Presumed Asymptomatic Carrier Transmission of COVID-19JAMA, 2020
- Insights into the Recent 2019 Novel Coronavirus (SARS-CoV-2) in Light of Past Human Coronavirus OutbreaksPathogens, 2020
- Preliminary Identification of Potential Vaccine Targets for the COVID-19 Coronavirus (SARS-CoV-2) Based on SARS-CoV Immunological StudiesViruses, 2020
- Cross‐species transmission of the newly identified coronavirus 2019‐nCoVJournal of Medical Virology, 2020
- ChAdOx1 and MVA based vaccine candidates against MERS-CoV elicit neutralising antibodies and cellular immune responses in miceVaccine, 2017
- Molecular Evolution of Human Coronavirus GenomesTrends in Microbiology, 2017
- Virus-Specific Memory CD8 T Cells Provide Substantial Protection from Lethal Severe Acute Respiratory Syndrome Coronavirus InfectionJournal of Virology, 2014
- Contributions of the structural proteins of severe acute respiratory syndrome coronavirus to protective immunityProceedings of the National Academy of Sciences, 2004
- Effects of a SARS-associated coronavirus vaccine in monkeysThe Lancet, 2003
- Efficacy of an Inactivated Vaccine against Clinical Disease Caused by Canine Coronavirus1995