The effect of endometriosis on oocyte quality: mechanisms, diagnosis and treatment
Open Access
- 1 February 2025
- journal article
- research article
- Published by Springer Nature in Archives of Gynecology and Obstetrics
- Vol. 311 (3) , 841-850
Abstract
Endometriosis significantly impacts the physical and mental health of women of reproductive age. While some patients can achieve pregnancy through surgery or in vitro fertilization (IVF), many still struggle with IVF failure due to poor oocyte quality. This presents a major clinical challenge that requires immediate attention. The causes of oocyte quality decline in endometriosis patients are diverse and have not yet been definitively identified. Furthermore, effective diagnostic mechanisms and therapeutic strategies remain elusive. To provide possible clinical solutions to improve pregnancy rates in patients with endometriosis, this review evaluates the current literature on the impact of endometriosis on oocyte quality, the possible mechanisms and management strategies of endometriosis leading to poor oocyte quality.Keywords
This publication has 94 references indexed in Scilit:
- Does endometriosis inflict harm on embryos? A systematic review of embryo morphokinetics analysed by time lapse monitoring in women with endometriosisArchives of Gynecology and Obstetrics, 2023
- Interleukin 6 in follicular fluid reduces embryo fragmentation and improves the clinical pregnancy rateJournal of Assisted Reproduction and Genetics, 2020
- Long-term GnRH agonist therapy before in vitro fertilisation (IVF) for improving fertility outcomes in women with endometriosisCochrane Database of Systematic Reviews, 2019
- Anti-inflammatory cytokines in endometriosisCellular and Molecular Life Sciences, 2019
- Oocyte oxidative DNA damage may be involved in minimal/mild endometriosis‐related infertilityMolecular Reproduction and Development, 2018
- Intrafollicular interleukin-8, interleukin-12, and adrenomedullin are the promising prognostic markers of oocyte and embryo quality in women with endometriosisJournal of Assisted Reproduction and Genetics, 2016
- Increased concentration of 8-hydroxy-2′-deoxyguanosine in follicular fluid of infertile women with endometriosisCell and tissue research, 2016
- Oxidative stress and oocyte quality: ethiopathogenic mechanisms of minimal/mild endometriosis-related infertilityCell and tissue research, 2015
- Effects of oxidative stress on embryonic developmentBirth Defects Research Part C: Embryo Today: Reviews, 2007
- Endometriosis is not detrimental to embryo implantation in oocyte recipientsJournal of Assisted Reproduction and Genetics, 1997