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  1. Home
  2. Publications
  3. Supplementary Figure S1 from The Combination of Trametinib and Ganitumab is Effective in RAS-Mutated PAX-Fusion Negative Rhabdomyosarcoma Models
  1. Home
  2. Publications
  3. Supplementary Figure S1 from The Combination of Trametinib and Ganitumab is Effective in RAS-Mutated PAX-Fusion Negative Rhabdomyosarcoma Models

Supplementary Figure S1 from The Combination of Trametinib and Ganitumab is Effective in RAS-Mutated PAX-Fusion Negative Rhabdomyosarcoma Models

Authors:
  • KHKatie E. Hebron
    Katie E. Hebron
  • XWXiaolin Wan
    Xiaolin Wan
  • JRJacob S. Roth
    Jacob S. Roth
  • DLDavid J. Liewehr
    David J. Liewehr
  • NSNancy E. Sealover
    Nancy E. Sealover
  • WFWilliam J.E. Frye
    William J.E. Frye
  • AKAngela Kim
    Angela Kim
  • SSStacey Stauffer
    Stacey Stauffer
  • OPOlivia L. Perkins
    Olivia L. Perkins
  • WSWenyue Sun
    Wenyue Sun
  • KIKristine A. Isanogle
    Kristine A. Isanogle
  • CRChristina M. Robinson
    Christina M. Robinson

Open Access
Publisher website
Google Scholar
  • 25 November 2025
    • other
    • Published by American Association for Cancer Research (AACR)
    • DOI:10.1158/1078-0432.30706052
Abstract
Combining ganitumab with trametinib inhibits tumor growth and increases fibrosis in SMS-CTR but not RD xenografts
Keywords
  • DRUG TARGETS
  • CELL SURFACE RECEPTOR DRUG TARGETS
  • PROTEIN KINASE & PHOSPHATASE DRUG TARGETS
  • PEDIATRIC CANCERS
  • PRECLINICAL MODELS
  • ANIMAL MODELS OF CANCER
  • TRANSLATIONAL RESEARCH
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