Permeability and Structure of Junctional Membranes at an Electrotonic Synapse
Authors:
- 26 December 1969
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 166 (3913) , 1641-1643
Abstract
The dye Procion Yellow M4RS crosses junctional membranes from cytoplasm to cytoplasm at electrotonic synapses between segments of the crayfish septate axon. The dye does not enter the cells from extracellular space. Thus permeability of junctional membranes is qualitatively different from that of nonjunctional membranes. Electron microscopy after fixation in the presence of lanthanum hydroxide indicates that these synapses are "gap junctions" and that there is a network of channels continuous with extracellular space between apposed junctional membranes. These channels must be interlaced with intercytoplasmic channels that are not open to extracellular space.Keywords
This publication has 14 references indexed in Scilit:
- JUNCTIONS BETWEEN INTIMATELY APPOSED CELL MEMBRANES IN THE VERTEBRATE BRAINJournal of Cell Biology, 1969
- Lateral Giant Fibers of Crayfish: Location of Somata by Dye InjectionScience, 1968
- Neuronal Geometry: Determination with a Technique of Intracellular Dye InjectionScience, 1968
- HEXAGONAL ARRAY OF SUBUNITS IN INTERCELLULAR JUNCTIONS OF THE MOUSE HEART AND LIVERJournal of Cell Biology, 1967
- Cell-to-Cell Passage of Large MoleculesNature, 1966
- PHYSIOLOGY OF ELECTROTONIC JUNCTIONS*Annals of the New York Academy of Sciences, 1966
- SPECIALIZED JUNCTIONS INVOLVED IN ELECTRICAL TRANSMISSION BETWEEN NEURONS.*Annals of the New York Academy of Sciences, 1966
- THE OCCURRENCE OF A SUBUNIT PATTERN IN THE UNIT MEMBRANES OF CLUB ENDINGS IN MAUTHNER CELL SYNAPSES IN GOLDFISH BRAINSJournal of Cell Biology, 1963
- Some observations on the fine structure of the giant fibers of the crayfishes (Cambarus virilus and Cambarus clarkii) with special reference to the submicroscopic organization of the synapsesThe Anatomical Record, 1961
- Impulse Propagation at the Septal and Commissural Junctions of Crayfish Lateral Giant AxonsJournal of General Physiology, 1961