Changes in activity of certain enzymes of the tricarboxylic acid cycle and the glyoxylate cycle during the initiation of conidiation of Aspergillus niger

Authors:
  • JGJ. C. Galbraith
    J. C. Galbraith
  • JSJ. E. Smith
    J. E. Smith
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Abstract
The activities of certain enzymes of the tricarboxylic acid (TCA) cycle and the glyoxylate cycle (GLC) varied during growth of Aspergillus niger as a function of the stage of the life cycle and of the growth medium. Isocitrate dehydrogenase (carboxylating) and isocitrate lyase each showed a marked increase in activity prior to sporulation. There were no similar increases in vegetative cultures. It is proposed that isocitrate lyase is functional in glycine synthesis and that a source of glyoxylate may be indispensable to the expression of sporulation.