Dependence on Na+ of control of cytoplasmic pH in a facultative alkalophile

Authors:
  • DMDebbie McLaggan
    Debbie McLaggan
  • MSMichael J. Selwyn
    Michael J. Selwyn
  • ADAlan P. Dawson
    Alan P. Dawson

Abstract
Regulation of the cytoplasmic pH of Exiguobacterium aurantiacum is dependent on the presence of Na+ in the medium. The data suggest that above 500 μM external Na+ the cells are able to regulate the cytoplasmic pH by the operation of a Na+ cycle involving a Na+/H+ antiport and a route for rapid Na+ entry. Our data indicate that the rate of entry of Na+ is subject to control by the cytoplasmic pH via feedback inhibition.

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