The Role of Phytonutrients in Skin Health
Open Access
Abstract
Photodamage is known to occur in skin with exposure to sunlight, specifically ultraviolet (UV) radiation. Such damage includes inflammation, oxidative stress, breakdown of the extracellular matrix, and development of cancer in the skin. Sun exposure is considered to be one of the most important risk factors for both nonmelanoma and melanoma skin cancers. Many phytonutrients have shown promise as photoprotectants in clinical, animal and cell culture studies. In part, the actions of these phytonutrients are thought to be through their actions as antioxidants. In regard to skin health, phytonutrients of interest include vitamin E, certain flavonoids, and the carotenoids, b-carotene, lycopene and lutein.Keywords
This publication has 144 references indexed in Scilit:
- Topical Delivery of Lycopene using Microemulsions: Enhanced Skin Penetration and Tissue Antioxidant ActivityJournal of Pharmaceutical Sciences, 2010
- Intake of antioxidant nutrients and the risk of skin cancerEuropean Journal of Cancer, 2007
- Protective effect against sunburn of combined systemic ascorbic acid (vitamin C) and d-α-tocopherol (vitamin E)Journal of the American Academy of Dermatology, 1998
- Inhibition of cyclobutane pyrimidine dimer formation in epidermal p53 gene of UV‐irradiated mice by α‐tocopherolNutrition and Cancer, 1997
- Prevention of photocarcinogenesis by topical administration of pure epigallocatechin gallate isolated from green teaNutrition and Cancer, 1996
- Importance of the form of topical vitamin E for prevention of photocarcinogenesisNutrition and Cancer, 1996
- Structure-antioxidant activity relationships of flavonoids and phenolic acidsFree Radical Biology and Medicine, 1996
- Hydrolysis of RRR-α-tocopheryl acetate (vitamin E acetate) in the skin and its UV protecting activity (an in vivo study with the rat)Journal of Photochemistry and Photobiology B: Biology, 1995
- Topical vitamin e inhibition of immunosuppression and tumorigenesis induced by ultraviolet irradiationNutrition and Cancer, 1991
- The influence of topical and systemic vitamin E on ultraviolet light‐induced skin damage in Hairless MiceNutrition and Cancer, 1991