Clinical and Economic Burden of Pneumococcal Disease Due to Serotypes Contained in the 20-Valent Pneumococcal Conjugate Vaccine in the Adult Population in France

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Abstract
Streptococcus pneumoniae causes invasive pneumococcal disease and pneumonia. This study models the burden of adult pneumococcal disease in France. Over a 5-year period, approximately 630,000 cases and €3.1 billion of costs were attributable to pneumococcus, mostly non-invasive disease, with nearly 80% due to serotypes included in 20-valent pneumococcal conjugate vaccine.