Secondary (additional) findings from the 100,000 Genomes Project: Disease manifestation, health care outcomes, and costs of disclosure
Authors:
Open Access
- 19 December 2023
- journal article
- research article
- Published by Elsevier in Genetics in Medicine
- Vol. 26 (3) , 101051
Abstract
No abstract availableKeywords
Funding Information
- Wellcome Trust
- NIHR Oxford Biomedical Research Centre
This publication has 48 references indexed in Scilit:
- Early cancer diagnoses through BRCA1/2 screening of unselected adult biobank participantsGenetics in Medicine, 2018
- “Not pathogenic until proven otherwise”: perspectives of UK clinical genomics professionals toward secondary findings in context of a Genomic Medicine Multidisciplinary Team and the 100,000 Genomes ProjectGenetics in Medicine, 2018
- Evaluation of Polygenic Risk Scores for Breast and Ovarian Cancer Risk Prediction in BRCA1 and BRCA2 Mutation CarriersJNCI: Journal of the National Cancer Institute, 2017
- Stakeholder views on secondary findings in whole-genome and whole-exome sequencing: a systematic review of quantitative and qualitative studiesGenetics in Medicine, 2017
- Genetic identification of familial hypercholesterolemia within a single U.S. health care systemScience, 2016
- The clinical application of genome-wide sequencing for monogenic diseases in Canada: Position Statement of the Canadian College of Medical GeneticistsJournal of Medical Genetics, 2015
- The cost-effectiveness of returning incidental findings from next-generation genomic sequencingGenetics in Medicine, 2014
- Precision Medicine Meets Public Health: Population Screening for BRCA1 and BRCA2JNCI: Journal of the National Cancer Institute, 2014
- ACMG recommendations for reporting of incidental findings in clinical exome and genome sequencingGenetics in Medicine, 2013
- Whole-genome sequencing in health careEuropean Journal of Human Genetics, 2013