Synthesis of a novel hydrazone-based compound applied as a fluorescence turn-on chemosensor for iron( iii ) and a colorimetric sensor for copper( ii ) with antimicrobial, DFT and molecular docking studies
Open Access
- 4 August 2023
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in RSC Advances
- Vol. 13 (34) , 23819-23828
Abstract
A novel molecule 5-bromo-2-hydroxy- N ′-[(1 E )-1-(thiophen-2-yl)ethylidene]benzohydrazide (L) has been designed and synthesized. The sensing studies of L showed a ratio metric & turn-on-enhanced fluorescence and colorimetric response toward Fe 3+ and Cu 2+ ions respectively.Keywords
This publication has 40 references indexed in Scilit:
- Design, synthesis, computational calculation and biological evaluation of some novel 2-thiazolyl hydrazonesSpectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2015
- Small-Molecule Library Screening by Docking with PyRx2014
- Unity in the Biochemistry of the Iron-Storage Proteins Ferritin and BacterioferritinChemical Reviews, 2014
- Synthesis and antifungal activity of substituted salicylaldehyde hydrazones, hydrazides and sulfohydrazidesBioorganic & Medicinal Chemistry, 2014
- Fluorescent Sensors for Measuring Metal Ions in Living SystemsChemical Reviews, 2014
- Toxicological effects of major environmental pollutants: an overviewEnvironmental Monitoring and Assessment, 2012
- Effect of substitution and planarity of the ligand on DNA/BSA interaction, free radical scavenging and cytotoxicity of diamagnetic Ni(ii) complexes: A systematic investigationDalton Transactions, 2011
- ATP7A-related copper transport diseases—emerging concepts and future trendsNature Reviews Neurology, 2011
- SWISS‐MODEL and the Swiss‐Pdb Viewer: An environment for comparative protein modelingElectrophoresis, 1997
- Use of Dipole Moment as a Parameter in Drug–Receptor Interaction and Quantitative Structure–Activity Relationship StudiesJournal of Pharmaceutical Sciences, 1982