An antibiotic concentration gradient microfluidic device integrating surface-enhanced Raman spectroscopy for multiplex antimicrobial susceptibility testing

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Abstract
We developed a microfluidic device to generate the concentration gradient of antibiotics along a series of lateral microwells to encapsulate bacteria and perform in situ multiplex surface-enhanced Raman scattering (SERS)-AST.
Funding Information
  • Ministry of Science and Technology, Taiwan (MOST 109-2639-M-001-005-ASP)
  • Ministry of Science and Technology, Taiwan (MOST 110-2221-E-002 -009 -MY3)

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