Deacylative Carbon‐Carbon Bond Cleavage of Ketone Equivalents: Applications to Radical Carbon‐Carbon Bond Formation Reactions

Authors:
Publisher website
Google Scholar
Abstract
This article describes the synthetic application of ketone‐derived oxaziridines as alkyl radical precursors in copper‐catalyzed Carbon‐Carbon bond formation reactions. Experimental and computational studies indicate a free radical mechanism, where alkyl radicals are efficiently generated via cleavage of a Carbon‐Carbon bond of oxaziridines. Acyclic and unstrained cyclic oxaziridines are applicable to the present radical process, allowing for the generation of various alkyl radicals with good functional group compatibility.

This publication has 59 references indexed in Scilit: