Loosenin-Like Proteins from Phanerochaete carnosa Impact Both Cellulose and Chitin Fiber Networks

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Abstract
The present study deepens investigations of microbial expansin-related proteins and their applied significance by (i) reporting a detailed comparison of diverse loosenins encoded by the same organism, (ii) considering both cellulosic and chitin-containing materials as targeted substrates, and (iii) investigating the impact of the C-terminal carbohydrate binding module (CBM) present in other expansin-related proteins on loosenin function. By revealing the potential of fungal loosenins to impact both cellulose and chitin-containing networks, our study reveals a possible biological and applied role of loosenins in fungal cell wall processing.
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Funding Information
  • EC | HORIZON EUROPE Framework Programme (964764)
  • EC | ERC | HORIZON EUROPE European Research Council (648925)
  • Novo Nordisk Fonden (34622)
  • U.S. Department of Energy (DE-FG02-84ER13179)
  • the academy of finland (311244)
  • WRI | Jenny ja Antti Wihurin Rahasto (Young Synbio Scientists)

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