ER Stress Causes Rapid Loss of Intestinal Epithelial Stemness through Activation of the Unfolded Protein Response
Authors:
- Jooske F. van Lidth de JeudeJJJooske F. van Lidth de Jeude
- Bon-Kyoung KooBKBon-Kyoung Koo
- Sanne L. RosekransSRSanne L. Rosekrans
- Mattheus C.B. WielengaMWMattheus C.B. Wielenga
- Marc van de WeteringMWMarc van de Wetering
- Marc FerranteMFMarc Ferrante
- Amy S. LeeALAmy S. Lee
- Jos J.M. OnderwaterJOJos J.M. Onderwater
- James C. PatonJPJames C. Paton
- Adrienne W. PatonAPAdrienne W. Paton
- A. Mieke MommaasAMA. Mieke Mommaas
Open Access
- 1 April 2013
- journal article
- Published by Elsevier in Cell Reports
- Vol. 3 (4) , 1128-1139
Abstract
No abstract availableKeywords
This publication has 32 references indexed in Scilit:
- The intestinal stem cell markers Bmi1 and Lgr5 identify two functionally distinct populationsProceedings of the National Academy of Sciences, 2011
- The critical role of GRP78 in physiologic and pathologic stressCurrent Opinion in Cell Biology, 2011
- Paneth cells constitute the niche for Lgr5 stem cells in intestinal cryptsNature, 2010
- A robust and high-throughput Cre reporting and characterization system for the whole mouse brainNature Neuroscience, 2009
- XBP1 Links ER Stress to Intestinal Inflammation and Confers Genetic Risk for Human Inflammatory Bowel DiseaseCell, 2008
- Dephosphorylation of Translation Initiation Factor 2α Enhances Glucose Tolerance and Attenuates Hepatosteatosis in MiceCell Metabolism, 2008
- Identification of stem cells in small intestine and colon by marker gene Lgr5Nature, 2007
- ER chaperones in mammalian development and human diseasesFEBS Letters, 2007
- Rapid Loss of Intestinal Crypts upon Conditional Deletion of the Wnt/Tcf-4 Target Gene c-MycMolecular and Cellular Biology, 2006
- GRP78/BiP Is Required for Cell Proliferation and Protecting the Inner Cell Mass from Apoptosis during Early Mouse Embryonic DevelopmentMolecular and Cellular Biology, 2006