Abstract
Laboratory investigations, including computed tomographic scan, and magnetic resonance imaging, were normal. A positron emission tomographic brain scan showed a slight bilateral frontal deficit. Cerebrospinal fluid leak analysis revealed a slight increase in protein but was otherwise normal, including a search for oligoclonal bands, infectious workup, and 14-3-3 protein analysis. An electroencephalogram showed slight cortical dysfunction. Complete metabolic workup was negative as was heavy metal screening. Family history was negative for neurologic disease. The postulated clinical diagnosis was Creutzfeldt-Jacob disease.

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