Quantitative Analysis of EEG Power Spectra in Experimental Hepatic Encephalopathy

Authors:
  • RPR.J. Popken
    R.J. Popken
  • DKD. Kropveld
    D. Kropveld
  • JOJ. Oosting
    J. Oosting
  • RCR.A.F.M. Chamuleau
    R.A.F.M. Chamuleau

Abstract
During galactosamine-induced acute liver failure in white male Wistar rats, EEG was recorded at regular intervals. Spectral analysis was done as described by Kropveld and co-workers in 1983. The specificity of the anomalies in the power-density spectra is tested by comparing the changing patterns with those caused by several pharmaceutical agents--ether, diazepam, pentobarbital. Quantification of the observed anomalies is discussed.

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