Independent differentiative pathways of Ly1 and Ly23 subclasses of T cells. Experimental production of mice deprived of selected T-cell subclasses.
Authors:
- B HuberBHB Huber
- H CantorHCH Cantor
- F W ShenFSF W Shen
- E A BoyseEBE A Boyse
Open Access
- 1 October 1976
- journal article
- research article
- Published by Rockefeller University Press in Journal of Experimental Medicine
- Vol. 144 (4) , 1128-1133
Abstract
When B mice are supplied with Ly1 or Ly23 cells they acquire, over the next 6 mo, only the immune functions associated with each of these T-cell subclasses, respectively. The T-cell population of these "B-Ly1" and "B-Ly23" mice mice also remains restricted to the Ly1 and Ly23 subclass phenotypes. Thus the Ly1 and Ly23 populations are derived from two separate lines of differentiation and are not sequential stages of a single differentiative pathway.Keywords
This publication has 5 references indexed in Scilit:
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