Two Bioactive Pentacyclic Triterpene Esters from the Root Bark of Hibiscus syriacus
Authors:
- 3 April 1999
- journal article
- research article
- Published by American Chemical Society (ACS) in Journal of Natural Products
- Vol. 62 (5) , 764-766
Abstract
Two new triterpene caffeates have been isolated from the root bark of Hibiscus syriacus. Their structures were established through various spectral studies as 3β,23,28-trihydroxy-12-oleanene 23-caffeate (1) and 3β,23,28-trihydroxy-12-oleanene 3β-caffeate (2). Compounds 1 and 2 showed lipid peroxidation inhibitory activity and significant cytotoxicity against a panel of human cancer cell lines.Keywords
This publication has 2 references indexed in Scilit:
- Synthesis of alternating hydroxy- and methyl-substituted hydrocarbons by oxymercuration of cyclopropylcarbinolsJournal of the American Chemical Society, 1986
- Assay for lipid peroxides in animal tissues by thiobarbituric acid reactionAnalytical Biochemistry, 1979