Improved Solubility and Oral Absorption of Emodin-Nicotinamide Cocrystal Over Emodin with PVP as a Solubility Enhancer and Crystallization Inhibitor
Authors:
- 1 December 2020
- journal article
- research article
- Published by Elsevier in Journal of Pharmaceutical Sciences
- Vol. 109 (12) , 3660-3667
Abstract
No abstract availableKeywords
Funding Information
- Ministry of Food and Drug Safety (16172MFD173)
This publication has 29 references indexed in Scilit:
- Coformer Selection in Pharmaceutical Cocrystal Development: a Case Study of a Meloxicam Aspirin Cocrystal That Exhibits Enhanced Solubility and PharmacokineticsJournal of Pharmaceutical Sciences, 2011
- Dependence of cocrystal formation and thermodynamic stability on moisture sorption by amorphous polymerCrystEngComm, 2010
- Species and Gender Differences Affect the Metabolism of Emodin via GlucuronidationThe AAPS Journal, 2010
- The Use of Biorelevant Dissolution Media to Forecast the In Vivo Performance of a DrugThe AAPS Journal, 2010
- Effects of Crystal Form on Solubility and Pharmacokinetics: A Crystal Engineering Case Study of LamotrigineCrystal Growth & Design, 2009
- The Co‐Crystal Approach to Improve the Exposure of a Water‐Insoluble Compound: AMG 517 Sorbic Acid Co‐Crystal Characterization and PharmacokineticsJournal of Pharmaceutical Sciences, 2008
- Cellular Absorption of Anthraquinones Emodin and Chrysophanol in Human Intestinal Caco-2 CellsBioscience, Biotechnology, and Biochemistry, 2007
- Evaluation of the antibacterial activity ofVentilago madraspatana Gaertn.,Rubia cordifolia Linn. andLantana camara Linn.: isolation of emodin and physcion as active antibacterial agentsPhytotherapy Research, 2005
- Role of Molecular Interaction in Stability of Celecoxib−PVP Amorphous SystemsMolecular Pharmaceutics, 2005
- Immune reponses in human mesangial cells regulatedLife Sciences, 2001